Abby (Amy Poehler) decides to celebrate her friend Rebecca’s (Rachel Dratch) 50th birthday with a weekend getaway over Rebecca’s protestations that she wants a low-key celebration. Abby, Rebecca and four of their friends, whom they have known since they were young waitresses, decide to spend the weekend together in Napa.
Rather than allow the women to relax and drink Abby wants them to adhere to a strict schedule, a way of seizing control as, unbeknownst to the rest of her friends, she has recently lost her job. All the other friends are struggling with problems of their own: Rebecca is in denial that her husband is inattentive and her friends hate him, Naomi (Maya Rudolph) is afraid of receiving test results from her doctor, successful business woman Catherine (Ana Gasteyer) feels that the rest of the friends are cutting her out, Val is looking for love and Jenny a depressive writer, is simply miserable in life.
On Friday the friends eat at an expensive restaurant where Val flirts with their waitress, Jade.
The following morning the women have a sinister tarot reading from a woman called Lady Sunshine. Afterwards they go day drinking around Napa. Near the end of their tour there is tension when Abby snaps at the other women for not adhering to their schedule. When Rebecca goes to talk to her about her attitude Abby reveals that she lost her job. In anger Abby throws out her schedule and the women decide to go to Jade’s art gallery opening.
Starring: Rachel Dratch, Ana Gasteyer, Amy Poehler, Maya Rudolph, Paula Pell, Emily Spivey, Cherry Jones, Maya Erskine, Jason Schwartzman, Tina Fey,